Basic Information:
With its unique molecular structure and physicochemical properties, hyaluronic acid shows a variety of important physiological functions in the body, such as lubricating joints, regulating the permeability of blood vessel wall, regulating the diffusion and operation of protein, water and electrolyte, and promoting wound healing. More importantly, hyaluronic acid has a special water retaining effect. It is the best moisturizing substance found in nature at present, and is called an ideal natural moisturizing factor
SPECIFICAIONS
| Item |
Specification |
Result |
| Physical & Chemical Test |
| Appearance |
White or almost white powder or granules |
Complies |
| Infrared absorption |
Positive |
Complies |
| Reaction of sodium |
Positive |
Complies |
| Absorbance |
≤0.25 |
0.08 |
| Transparency |
≥99.0% |
100.0% |
| PH |
6.0~7.5 |
6.5 |
| Intrinsic viscosity |
≥22.40 dL/g |
22.66 dL/g |
| Molecular weight |
≥1.40×106 Da |
1.42×106 Da |
| Kinematic viscosity |
Actual value |
52.57 mm²/s |
| Purity Test |
| Loss on drying |
≤10% |
9.34% |
| Residue on ignition |
≤20% |
18.85% |
| Heavy metals |
≤20ppm |
<20ppm |
| Arsenic |
≤2ppm |
<2ppm |
| Protein |
≤0.1% |
0.03% |
| Assay |
95.0%~105.0% |
96.6% |
| Glucuronic acid |
46.0%~51.0% |
46.7% |
| Microbiological Purity |
| Total bacterial count |
≤100CFU/g |
<10CFU/g |
| Yeasts & mold |
≤20CFU/g |
<10CFU/g |
| E.coli |
Negative |
Negative |
| Staph |
Negative |
Negative |
| Pseudomonas aeruginosa |
Negative |
Negative |
| Conclusion: The product above complies with the standard of QB/T 4416-2012. |
Cosmetics: Sodium hyaluronate is widely used in cosmetics as a moisturizing and anti-aging agent. It is added to various skincare products, such as creams, serums, and masks, to help improve skin hydration and reduce the appearance of fine lines and wrinkles. Sodium hyaluronate is also used in hair care products to enhance hydration and elasticity.
Dermal Fillers: Sodium hyaluronate is used in injectable dermal fillers to help restore volume to areas of the face that have lost fat or collagen. Dermal fillers containing sodium hyaluronate are injected into the skin, where they add volume and smooth out wrinkles and fine lines. The effects of these fillers typically last several months to a year, depending on the product and the individual.
Ophthalmology: Sodium hyaluronate is used in ophthalmology as a viscoelastic agent during eye surgery. It helps to maintain the shape of the eye during surgery and also helps to protect the cornea from damage. Sodium hyaluronate is also used in some contact lens solutions to improve lens comfort and hydration.
Wound Healing: Sodium hyaluronate is used in wound healing as a dressing or spray. It helps to keep the wound moist and prevent the formation of scabs, which can impede recovery. Sodium hyaluronate is also believed to have anti-inflammatory properties, which can help to reduce pain and swelling associated with wounds.
Joint Injections: Sodium hyaluronate is used in injections to treat joint disorders like osteoarthritis. Injections of sodium hyaluronate into the joint can help to lubricate the joint, reduce inflammation, and improve mobility.
Drug Delivery: Sodium hyaluronate is being investigated as a drug delivery vehicle for various drugs, including chemotherapy. The large size of the sodium hyaluronate molecule makes it ideal for encapsulating drugs and delivering them to specific tissues or cells. Sodium hyaluronate can also help prolong drug release, making them more effective.
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